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Cauda Equina Compression

Summary

  • Compression of nerve roots below L1-L2 spinal level
  • Caused by space-occupying lesions in the spinal canal
  • Presents with lower back pain, saddle anesthesia, and bladder/bowel dysfunction1

Pathophysiology

  • Compression of lumbosacral nerve roots within the spinal canal
  • Common causes:
    • Herniated lumbar disc (most frequent)
    • Spinal stenosis
    • Tumour (primary or metastatic)
    • Trauma
    • Epidural abscess or haematoma
  • Leads to ischaemia and potential permanent nerve damage if not treated promptly

Demographics

  • Incidence: 1-3 cases per 100,000 population per year
  • Most common in adults aged 30-50 years
  • Slightly more prevalent in males
  • Risk factors:
    • Degenerative disc disease
    • History of spinal surgery
    • Spinal trauma
    • Coagulopathies (for epidural haematoma)

Diagnosis

  • Clinical presentation:
    • Low back pain
    • Bilateral sciatica
    • Saddle anesthesia
    • Bladder and/or bowel dysfunction
    • Lower extremity weakness
  • Physical examination:
    • Reduced perianal sensation
    • Decreased anal sphincter tone
    • Lower extremity motor and sensory deficits
  • Diagnostic criteria:
    • One or more of: bladder/bowel dysfunction, reduced sensation in saddle area, sexual dysfunction
    • Plus one or more of: low back pain, bilateral sciatica, lower extremity sensorimotor deficits

Imaging

  • MRI:
    • Gold standard for diagnosis
    • T1-weighted: assess vertebral body alignment and marrow changes
    • T2-weighted: evaluate disc herniations, spinal cord, and nerve root compression
    • Gadolinium-enhanced: useful for detecting tumours or infections
  • CT myelography:
    • Alternative when MRI is contraindicated
    • Shows compression of nerve roots and thecal sac
  • Plain radiographs:
    • Limited utility, may show vertebral body misalignment or fractures
  • CT:
    • Useful for assessing bony abnormalities and fractures

panels-1

  • 50-year-old patient presented with acute onset severe sciatica.
  • At L4-5, a cranially migrated disc extrusion caused effacement of all CSF and compression of the cauda equina.

Treatment

  • Urgent surgical decompression, ideally early, for progressive deficit
  • Directed at the cause (discectomy, tumour resection, abscess/haematoma evacuation)

Differential diagnosis (compressive/enhancing cauda equina)

Imaging differential Differentiating feature
Central disc extrusion Disc-signal material effacing the thecal sac, contiguous with the parent disc
Epidural abscess Rim-enhancing epidural collection, often with adjacent discitis and endplate erosion
Epidural haematoma Non-enhancing epidural collection with blood-product signal; anticoagulation/procedure history
Epidural metastasis / lymphoma Enhancing marrow-replacing or epidural soft tissue with cord/root compression
Drop metastases / leptomeningeal disease Nodular enhancing deposits coating the roots rather than a single compressive mass
Guillain-Barré / CIDP Smooth thickening and enhancement of the roots without a compressive lesion

  1. B Rydevik. Neurophysiology of cauda equina compression. 1993. Acta orthopaedica Scandinavica. Supplementum - Open in new tab