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Case of the month¶
July 2026
- 55-year-old patient presented with the sudden onset of anterograde amnesia lasting several hours, with no focal neurological deficit.
- What is the diagnosis?
Click to reveal the answer
Transient Global Amnesia (TGA)
- DWI showed a punctate focus of diffusion restriction in the lateral hippocampus.
- These characteristic 1-3 mm dots are best seen 24-72 hours after symptom onset and may be absent if imaged too early.
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Transient global amnesia is a self-limiting clinical syndrome of isolated anterograde memory loss resolving within 24 hours; the punctate hippocampal CA1 DWI lesion confirms the diagnosis and helps exclude infarct or limbic encephalitis.